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5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
ABT-594 is orally active
Formula: C32H46N6O7S
CAS Number: 2648089-95-4
The 5-day regimen at 10 mg/kg/day protected 50% of mice
TCS HDAC6 20b Size:Contact [email protected] for quotation 5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amineTCS HDAC6 20b is a potent and selective inhibitor of histone deacetylase 6 (HADC6) . Histone deacetylases (HADC) are a series of enzymes that remove acetyl groups from an N acetyl lysine amino acid on a histone and make the histones to wrap the DNA more tightly, which prevent transcription. Mutation of HADC6 is associated with Alzheimer's disease. In HCT116 cells, TCS HDAC6 20b increased tubulin acetylation in a dose dependent way without a
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