Procyanidin B3 (racemic) InChi: InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8

InChi: InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8

PD-1/PD-L1-IN 3 blocks the binding of recombinant PD-L1-Ig to Jurkat-PD-1 cells

Cancer Discov

Smiles: NC(=N)NC(=O)CC1C(Cl)=CC=CC=1Cl

leaving normal cells almost unaffected

Procyanidin B3 (racemic) InChi: InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300 mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase). Product information CAS Number: 23567 23 9 Molecular Weight: 578. 52 Formula: C30H26O12 Chemical Name: (2R,3S,4S) 2 (3,4 dihydroxyphenyl) 4 [(2R,3S) 2 (3,4 dihydroxyphenyl) 3,5,7