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Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 1527473-33-1

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Description

1527473-33-1

PIK-93 (250 nM) effectively abrogates the accumulation of CERT-PH domain and FL-Cer in Golgi

is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML)

It results in vacuolation of lysosomes (A) and complete inhibition of the surface expression of Lamp-1

demonstrates potent antimigratory and anti-invasive effects in vitro

Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 1527473-33-1Dolutegravir, also known as GSK1349572, is a potent inhibitor of HIV integrase with an IC50 value of 2. 7 nM for HIV 1 integrase catalyzed strand transfer in vitro. 1 It inhibits HIV 1 viral replication (EC50 = 0. 51 nM) in peripheral blood mononuclear cells (PBMCs). Dolutegravir (DTG) is an antiretroviral medication used, together with other medication, to treat HIV AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV

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