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5 mg/mL (232
03-10 µM) potently prevents the growth-inhibitory effects of TGF-β
Chemical Name: 6-(3-fluorophenyl)-N-[1-(2
InChi: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38
Chemical Name: tert-butyl 3-{3-[3-(tert-butoxy)-3-oxopropoxy]-2-{[(tert-butoxy)carbonyl]amino}propoxy}propanoate
CU-3 aflumizone 5 mg/mL (232CU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS
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