5-Isoquinolinediol is a potent PARP antagonist and decreases cleaved PARP in diabetic retina
InChi: InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6
InChi: InChI=1S/C23H40N2O3/c26-21(27)10-8-6-4-2-1-3-5-7-9-11-24-22(28)25-23-15-18-12-19(16-23)14-20(13-18)17-23/h18-20H
FIIN-2 shows good potency against gatekeeper mutant V564F
InChiKey: ANQWETXPBPZVOF-UHFFFAOYSA-N
Tetrazine-Ph-PEG5-NHS ester Size:Contact [email protected] for quotation 5-Isoquinolinediol is a potent PARPTetrazine Ph PEG5 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1682653 80 0 Molecular Weight: 604. 61 Formula: C27H36N6O10 Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 ({[4 (1,2,4,5 tetrazin 3 yl)phenyl]methyl}carbamoyl) 3,6,9,12,15 pentaoxaoctadecan 18 oate Smiles: O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)NCC1C=CC(=CC=1)C1N=NC=NN=1 InChiKey: DUPHIQYIPUTDJS UHFFFAOYSA N InChi: