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Z-VAD-FMK ID 1375606 InChi: InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11

SKU: 93605317682

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Description

InChi: InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11

EPZ015666 was used at 5 µM final concentration in various in vitro assays

(2010) Bioorg Med Chem

it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex

CAS Number: 432001-19-9

Z-VAD-FMK ID 1375606 InChi: InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11Z VAD FMK (Z VAD(OH) FMK) is a well know pan caspase inhibitor, which does not inhibit ubiquitin carboxy terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 M. Product information CAS Number: 161401 82 7 Molecular Weight: 453. 46 Formula: C21H28FN3O7 Synonym: Z VAD(OH) FMK Chemical Name: (3S) 3 [(2S) 2 [(2S) 2 {[(benzyloxy)carbonyl]amino} 3 methylbutanamido]propanamido] 5 fluoro 4 oxopentanoic acid Smiles:

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