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is an endothelin receptor antagonist
CAS Number: 923288-90-8
It has no activity on the related receptors ERRα
It can induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes
increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium
Estramustine (phosphate sodium) eclizine dihydrochloride is an endothelin receptor antagonistEstramustine phosphate sodium is a synthetic molecule that combines estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose dependent fashion. This agent also exhibits anti androgenic effects. Check for active clinical trials or closed clinical trials using
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