Ispinesib (SB-715992) st N-oxide InChi: InChI=1S/C30H22F6N6O5/c31-29(32

Name: Ispinesib (SB-715992) st N-oxide InChi: InChI=1S/C30H22F6N6O5/c31-29(32
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SKU: 94259548813

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Description

InChi: InChI=1S/C30H22F6N6O5/c31-29(32

Genes Brain Behav

14(19):3101-11

75(6):1588-1590

8(4):467-479

Ispinesib (SB-715992) st N-oxide InChi: InChI=1S/C30H22F6N6O5/c31-29(32Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be

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