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ABT-888 dihydrochloride - CAS# 912445-05-7 0109 c-Met inhibitor INCB28060 selectively binds

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Description

c-Met inhibitor INCB28060 selectively binds to c-Met

11(15):3170-3

Epub 2014 May 13

BPTES-NPs (BPTES nanoparticles

InChiKey: HWNUSGNZBAISFM-UHFFFAOYSA-N

ABT-888 dihydrochloride - CAS# 912445-05-7 0109 c-Met inhibitor INCB28060 selectively bindsABT 888 dihydrochloride, also known asVeliparib, CAS No. 912445 05 7, is a potent and selective Poly (ADP Ribose) Polymerase (PARP) Inhibitor. ABT 888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT 888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5. 2 and 2. 9 nM, respectively). Product information CAS Number: 912445 05 7

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