Yes, there's a difference.) You can target a creature with no abilities other than keywords with TL;DR, but when TL;DR resolves, it won't exile that creature
Inspired by the Escape ability on the original Kroxa, when Kroxa or Kunoros enters the battlefield or attacks, you can exile five cards from your graveyard to resurrect a creature from there
Ive forgotten a lot of things over the years, but I havent forgotten the majority of the cards that made up my mono red deck from 1994
If you choose the second mode and your creature is not a legal target as Archdruid's Charm resolves, you won't put a +1/+1 counter on it, and no damage will be dealt
To make it easier to jump in with friends, most sets get preconstructed Commander Decks built around a specific theme or playstyle
For their sake, here are the details