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You can stop your opponents monster effects, disrupt their Summoning strategy by making a monster unusable as material, or make it indestructible while its stuck in Attack Position so you can run over it again and again to smash their Life Points
While the breadth of Modern discard makes this less of a problem, there are still matchups where Thoughtseize isn't very good, such as against decks like Dredge that want cards in their graveyard or against Burn, where the damage you take is relevant
2025-09-19 If an effect allows you to play a land or cast a spell from among a group of cards, you may play or cast a modal double-faced card with any face that fits the criteria of that effect
Deadeye Navigator quickly becomes the most worrisome threat when it enters the battlefield across the table from you
This is usually done via the Rob Lucci Character card from Awakening of the New Era [OP-05]