In effect, this means players are bidding on the number of troops they are willing to sacrifice to potentially win a province
If you need a general board wipe later in the game, cast Earth and put enough mana into the X cost to make it happen
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It suddenly capped off the cycle of Guildgates with an alternate win condition that demanded you play five colors (or close to it)
Along similar lines, the card is definitely worse in sideboarded games where most decks are more likely to draw that key piece of interaction, and the more copies of Unsubstantiate you play, the harder it is to sideboard them out when you decide theyre bad against your opponents post-sideboard configuration
And Mental Misstep is the ultimate tempo card, countering key 1-drops like Sol Ring, Mystic Remora, or Vampiric Tutor before your opponent can even get going