While it won't kill the biggest creatures by itself, 4 damage is enough to pick off most utility creatures from Crypt Ghast to Oracle of Mul Daya
(See: Sheoldred, the Apocalypse) So when were looking at price trends, we want to find cards that arent seeing much use in other formats
5 Ulamog, the Ceaseless Hunger I like creatures that are great to ramp up to and have some form of built-in protection like indestructible
Typal decks should consider Raise the Palisade, which is a way to help push damage through and reset the board, without interfering with your own deployment
Inkmoth Nexus is the easiest call, but people caught on to that one as soon as the full spoiler dropped, and the price is already through the roof
But it can also become a pretty good source of removal and interaction