You dont need other effects to deal with Ponders downsides
Non-combat related ways to dish out poison counters are also important for any infect strategy and Reaper of Sheoldred, Vraska's Fall, Bloodroot Apothecary, and Venerated Rotpriest do some dirty work
-- If multiple players each control one or more Knowledge Pools, the active player put their triggered abilities on the stack in any order, then each other player in turn order does the same
The reason people have this misconception is because random events tend to average out after several iterations
Additionally, Losheel notably comes along with card draw, allowing you to draw a card once per turn when an artifact creature enters the battlefield under your control for the first time each turn
Building around delirium is possible, but the hard delirium payoffs arent actually worth it