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Chemical Name: 5-(4
likely occupying a similar site within the ligand-binding domain
51(1):17-20
Molecular Weight: 417
SB-505124 selectively and concentration-dependently inhibits ALK4-
Rolapitant - CAS# 552292-08-7 Catalog No.:M6632-10 Chemical Name: 5-(4Rolapitant, CAS No. 552292 08 7, also known as SCH 619734, is an orally bioavailable, centrally acting, selective, neurokinin 1 receptor (NK1 receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1 receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP induced emesis and
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